Biochemistry

Courses for BIOC (BIOC)

AGRO 810
Plant Molecular Biology LINKCrosslisted as BIOS 810, BIOC 810, HORT 810
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
AGRO 315 or BIOS 206; BIOC 831 or permission
Molecular genetic basis of biological function in higher plants. Genome organization, gene structure and function, regulation of gene expression, recombinant DNA, and genetic engineering principles. Material taken primarily from current literature.
AGRO 818
Agricultural Biochemistry LINKCrosslisted as BIOC 818
Credit Hours: 2
Campus:
Course Delivery: Classroom
Prereqs:
Undergraduate major in life sciences or related area, and a course in biochemistry
A Web-based course. Biochemical underpinnings of agricultural production and processing systems. Agricultural biotechnology; bioenergetics; kinetics and enzyme regulation; interaction of biomolecules with light, photosynthesis and the balance between anabolism and catabolism in microbes, plants and animals.
ASCI 949
Biochemistry of Nutrition LINKCrosslisted as BIOS 949, BIOC 949, NUTR 949
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
BIOC 832 or *839, or permission
Offered odd-numbered calendar years. Interrelationships of nutrients, nutritional state and metabolic processes. Energy metabolism, integration of nutrition and metabolism and nutritional regulation of gene function.
BIOC 431/831
Biomolecules and Metabolism LINKCrosslisted as BIOS 431/831, CHEM 431/831
Credit Hours: 4
Course Format: Lecture 4
Course Delivery: Classroom
Prereqs:
CHEM 252 or 262. LIFE 120 recommended.
First course of a two-semester, comprehensive biochemistry course sequence.
Structure and function of proteins, nucleic acids, carbohydrates and lipids; nature of enzymes; major metabolic pathways; and biochemical energy production.
BIOC 432/832
Gene Expression and Replication LINKCrosslisted as BIOS 432, CHEM 432/832
Credit Hours: 2
Course Format: Lecture 2
Course Delivery: Classroom
Prereqs:
Continuation of BIOC 431/831. Structural and biochemical aspects of DNA replication and gene expression, and biotechnology.
BIOC 433/833
Biochemistry Laboratory LINKCrosslisted as BIOS 433/833, CHEM 433/833
Credit Hours: 2
Course Format: Lab 4, Lecture 1
Course Delivery: Classroom
Prereqs:
BIOC 431/831 or concurrent enrollment.
Introduction to techniques used in biochemical and biotechnology research, including measurement of pH, spectroscopy, analysis of enzymes, chromatography, fractionation of macromolecules, electrophoresis, and centrifugation.
BIOC 434/834
Plant Biochemistry LINKCrosslisted as BIOS 434/834, CHEM 434/834, AGRO 434/834
Credit Hours: 3
Course Format: Lecture 3
Course Delivery: Classroom
Prereqs:
BIOC/BIOS/CHEM 431/831.
Offered every other year beginning spring 2007.
Biochemical metabolism unique to plants. Relationships of topics previously acquired in general biochemistry to biochemical processes unique to plants. Biochemical mechanisms behind physiological processes discussed in plant or crop physiology.
BIOC 437/837
Research Techniques in Biochemistry LINKCrosslisted as BIOS 437/837
Credit Hours: 4
Course Format: Lab 3, Lecture 3
Course Delivery: Classroom
Prereqs:
BIOC/BIOS/CHEM 433/833, or permission.
Methods approach to systems biology analysis. Molecular identification and quantification employing techniques such as mass spectrometry, chromatography, electrophoretic fractionation, transcriptomics, protemics and metabolomics. Data and pathway analysis with computational methods.
BIOC 486/886
Advanced Topics in Biophysical Chemistry LINKCrosslisted as BIOS 486/886, CHEM 486/886
Credit Hours: 3
Course Format: Lecture 3
Course Delivery: Classroom
Prereqs:
Applications of thermodynamics to biochemical phenomena, optical properties of proteins and polynucleotides, and kinetics of rapid reactions.
BIOC 836
Physical Basis of Macromolecular Function LINKCrosslisted as CHEM 836
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Introduction to the theory and practice of biophysical characterization of macromolecules.  The course will be based on primary research literature, although a supporting text will be used for in depth discussion of the methods.
BIOC 839
Survey of Biochemistry LINKCrosslisted as BIOS 839, CHEM 839
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
Permission
Comprehensive survey of biochemistry for incoming graduate students. Topics include those in BIOC 831 and 832, but not all topics discussed in lecture periods. Depth enhanced by assigned readings.
BIOC 848
Redox Biochemistry LINKCrosslisted as CHEM 848
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
3 hrs BIOC and 3 hrs inorganic chemistry
Redox (oxidation and reduction)-based biochemical processes (energy generation, oxygen transfer, enzyme catalysis, signaling, gene regulation, and diseases). Recent progress in these areas. Roles of metals in biochemical reactions, metal homeostasis, and biosynthesis of metal cofactors and metal sites. Biochemistry and pathophysiology of redoxactive species and radicals. Antioxidant molecules and enzymes.
BIOC 869
Chemistry for Secondary School Classrooms LINKCrosslisted as BIOS 883, CHEM 869, TEAC 869
Credit Hours: 1
Max credits per degree: 12
Campus:
Course Delivery: Classroom
Credit in this course will not count towards a graduate degree in chemistry or biochemistry or biological sciences. Course taught via World Wide Web. Chemistry content for high school teachers organized according to the National Science Education Standards. Individual course coverage includes: content, integration with other sciences and mathematics, graphing calculators, probe-experiments, simulations, at-home experiments, teaching materials, and industrial applications related to the title description.
A. Structure and Properties of Matter: Water and Solutions (1 cr)
B. Structure and Properties of Matter: Periodicity (1 cr)
D. Structure and Properties of Matter: Bonding and Structure (1 cr)
E. Structure and Properties of Matter: Carbon Chemistry and Polymers (1 cr)
J. Structure and Properties of Matter: Gases and the Atmosphere (1 cr)
K. Chemistry of Life Processes: Biomolecules (1 cr)
L. Structure and Properties of Matter: Condensed States and Materials Science (1 cr)
M. Interactions of Matter and Energy (1 cr)
N. Chemistry of Life Processes: DNA (1 cr)
P. Chemistry of Life Processes: Energy and Metabolism (1 cr)
Q. Chemical Reactions: Equations and their Consequences (1 cr)
R. Chemical Reactions: Acids and Bases (1 cr)
T. Chemical Reactions: Kinetics (1 cr)
U. Chemical Reactions: Oxidation, Reduction and Electrochemistry (1 cr)
V. Equilibrium: Unifying Theme (1 cr)
W. Conservation of Energy and the Increase in Disorder: Thermodynamics (1 cr)
Y. Inquiry and the Nature of Science: Analysis and Instrumentation (1 cr)
Z. Structure of Atoms: Nuclear Chemistry (1 cr)
BIOC 898
Research in Biochemistry LINK
Credit Hours: 1-6
Campus:
Course Delivery: Classroom
Prereqs:
BIOC 833 and permission
Laboratory research on a specific problem under the supervision of a biochemistry faculty member.
BIOC 899
Masters Thesis LINK
Credit Hours: 6-10
Campus:
Course Delivery: Classroom
Prereqs:
Admission to masters degree program and permission of major adviser
BIOC 992K
Seminar in Biological Chemistry LINKCrosslisted as CHEM 992K
Credit Hours: 1-2
Max credits per degree: 2
Campus:
Course Delivery: Classroom
Prereqs:
BIOC 832 or *839; and permission
BIOC 998
Advanced Topics in Biochemistry LINK
Credit Hours: 1-3
Max credits per degree: 3
Campus:
Course Delivery: Classroom
Prereqs:
BIOC 832 and *839
BIOC 998 is a special biochemistry topics when faculty and student needs cannot be met by other courses.
BIOC 999
Doctoral Dissertation LINK
Credit Hours: 1-24
Max credits per degree: 55
Campus:
Course Delivery: Classroom
Prereqs:
Admission to doctoral degree program and permission of supervisory committee chair
CHEM 932
Proteins LINKCrosslisted as BIOS 932, BIOC 932
Credit Hours: 2
Course Format: Lecture 2
Campus:
Course Delivery: Classroom
Prereqs:
BIOC/BIOS/CHEM 832 or BIOC/BIOS/CHEM *839
Protein structure and function.
CHEM 933
Enzymes LINKCrosslisted as BIOS 933, BIOC 933
Credit Hours: 2
Course Format: Lecture 2
Campus:
Course Delivery: Classroom
Prereqs:
BIOC/BIOS/CHEM 432/832, or BIOC/BIOS/CHEM *839
Kinetics regulation and reaction mechanisms of enzymes.
CHEM 934
Genome Dynamics and Gene Expression LINKCrosslisted as BIOS 934, BIOC 934
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
BIOC/BIOS/CHEM 832 or permission
Detailed examination of dynamic control mechanisms of genome maintenance and gene regulation. Mechanisms of transcription, translation, and replication based on analysis of current and seminal literature.
CHEM 935
Metabolic Function and Dysfunction LINKCrosslisted as BIOS 935, BIOC 935
Credit Hours: 3
Course Format: Lecture 3
Campus:
Course Delivery: Classroom
Prereqs:
BIOC/CHEM/BIOS 432/832 and permission
BIOC/CHEM/BIOS 935 is offered even-numbered calendar years.
Current metabolic research at the bioenergetic, metabolomic, and molecular level. The normal metabolic processes that go awry in cancer, obesity, and oxidative stress.
STAT 442/842
Computational Biology LINKCrosslisted as BIOC 442/842
Credit Hours: 3
Course Format: Lab 2, Lecture 1
Course Delivery: Classroom
Prereqs:
Any introductory course in biology, or genetics, or statistics.
Databases, high-throughput biology, literature mining, gene expression, next-generation sequencing, proteomics, metabolomics, systems biology, and biological networks.

Description

For a brief description of the program, application requirements and contact information, view the graduate program summary.

Director for the Center for Biological Chemistry: Paul N. Black, Ph.D.

Graduate Chair: Melanie Simpson, Ph.D.

Graduate study in biochemistry is pursued through the Center for Biological Chemistry, which has responsibility for instructional programs, undergraduate degrees, and graduate degrees in biochemistry. The purpose of the program is to provide training in biochemistry that will prepare students for professional careers in agricultural, biomedical or natural sciences, with particular emphasis on carrying out and interpreting contemporary research. The program is designed to provide sufficient depth that the student will be at the state of the art in his/her area of specialization. At the same time, the program is designed to provide sufficient breadth that the student can understand current studies in related areas of biochemistry.

The faculty of the Center for Biological Chemistry is made up of faculty in Nutrition and Health Sciences, Agronomy and Horticulture, Biological Sciences, Chemistry, and Veterinary and Biomedical Sciences.

Applicants for graduate work in the Center for Biological Chemistry must have a BS or BA degree in biochemistry, biology, chemistry, or a related field. Undergraduate work should include at least one course in biochemistry, one course in genetics, one course in physical chemistry (calculus based), one year of organic chemistry, and one year of physics. Deficiencies in these requirements will be made up during the first year of graduate study. The verbal, quantitative and analytical parts of the Graduate Record Examination are required for a student to be considered for admission. The advanced Graduate Record Examination in biochemistry, biology, or chemistry is recommended. Foreign students whose native language is not English must have a minimum TOEFL score of 550.

Further information about admission and graduate programs can be obtained from the Center for Biological Chemistry, N200 Beadle Center, City Campus. Also visit the biochemistry Web site at biochem.unl.edu.

Master of Science Degree.

All students must take BIOC 836, 932, 933, 934, 935, and at least 4 credits of biochemistry seminar (BIOC 992K). Other course requirements are arranged in consultation with the Examining Committee. Students under Option I (advance permission is required to use Option II) must earn a minimum of 30 hours of credit, consisting of 20 to 24 hours of courses (including seminar) and 6 to 10 hours of thesis credit. At least one half of the required hours (including thesis) must be taken in the Center. At least 8 hours must be taken in courses only open to graduate students (900 level or 800 level without a 400 counterpart). Students will be required to assist with teaching biochemistry courses for a minimum of one semester.

Each student must pass a written comprehensive examination formulated and administered by the Examining Committee. The purpose of the exam is to test the student’s breadth of knowledge in biochemistry.

Students in the Option I program must complete an original research project, write a thesis, and present a publicized seminar open to faculty and students at which the work comprising the MS thesis is presented. Each student must pass a final oral examination administered by the Examining Committee.

Doctor of Philosophy Degree.

The PhD in the Center for Biological Chemistry is a research degree providing in-depth education in an area of biochemistry. Course requirements are arranged in consultation with the student’s Supervisory Committee but should include credit hours in BIOC 836, 932, 933, 934, 935 and 8 credits in biochemistry seminar (BIOC 992K).

Students must pass a comprehensive examination consisting of written and oral components. This examination will include preparation and defense of an original research proposal and the student’s Supervisory Committee is responsible for administering the exam.

Students must complete an original research project, write a dissertation, formally present and defend the research work in a seminar, and pass a final oral examination covering the research work and thesis administered by the Supervisory Committee. The PhD degree is principally a research degree; thus, this is the most important requirement in the program.

Minor in Biochemistry.

To fulfill the requirements for a minor in biochemistry, graduate students outside the Center for Biological Chemistry seeking a masters degree are required to complete at least 9 credits in BIOC-listed or cross-listed courses at the 800 or 900 level, with at least 3 credits at the 900 level. Students seeking a doctoral degree must complete at least 15 credits in BIOC-listed or cross-listed courses at the 800 or 900 level with at least 6 credits at the 900 level (for the doctoral degree).

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