*805. Introduction to Mechanisms of Disease (3 cr I) Lec 3.
Prereq: ASCI 240 or equivalent, BIOC/BIOS/CHEM 831, VBMS/BIOS 841, or permission
Offered odd-numbered calendar years. Designed for students of biological, animal, and veterinary sciences. Introduction to general pathology emphasizing etiology, pathogenesis, morphologic features, and fundamental alterations associated with the fundamental changes of disease.
808. Functional Histology (BIOS 808) (4 cr II) Lec 3, lab 2.
Prereq: BIOS 101 and 101L, or 102 or 112; BIOS 213 or ASCI 240
Recommended BIOS 315. Microscopic anatomy of the tissues and organs of major vertebrate species, including humans. Normal cellular arrangements of tissues and organs as related to their macroscopic anatomy and function, with reference to sub-cellular characteristics and biochemical processes. Functional relationships among cells, tissues, organs and organ systems, contributory to organismal well being. General introduction to pathological processes and principles underlying some diseases.
*811. Introduction to Veterinary Epidemiology (2 cr)
Prereq: Permission
Offered summer semester of odd-numbered years. Introduction to concepts of epidemiology including definition and uses of epidemiology. Casual web theory of causation discussed and compared to the Henle-Koch postulates. Students use sampling methods to define population characteristics, detect disease and test hypotheses. Practical application of confidence, power, and sample size. Use of descriptive epidemiology to discuss population characteristics.
816. Veterinary Entomology/Ectoparasitology (ASCI 816; ENTO 816; NRES 816) (2 cr II) Lec 2.
Prereq: 10 hrs entomology or biological science or related fields or permission
Arthropods that cause or vector diseases in animals. Arthropod recognition and biology, and disease epidemiology.
816L. Veterinary Entomology/Ectoparasitology Lab (ASCI 816L; ENTO 816L; NRES 816L) (1 cr II)
Prereq: ASCI, NRES, VBMS 816; or parallel
*818. Computer-Aided Sequence Analysis Primer (BIOS *816) (2 cr I)
Prereq: BIOC 831 or BIOS 801 or 820
Introductory course in biological sequence display, analysis and manipulation with computers. Applied rather than theoretical aspects of different programs are emphasized providing skills to satisfy the analysis demands of molecular biology research. Students completing this course will be able to search, display and analyze the biological information content of macromolecules.
820. Molecular Genetics (BIOS 820) (3 cr)
Prereq: 12 hrs biological sciences including BIOS 206 or equivalent
Molecular basis of genetics. Gene structure and regulation; transposable elements; chromosome structure; DNA replication, repair mechanisms and recombination.
824. Basic Molecular Infectious Diseases (3 cr I) Lec 3.
Prereq: BIOS 312; AGRO 360 or equivalent; or permission
Offered spring semester of odd-numbered calendar years. Introduction to the molecular, genetic and cellular aspects of microbial pathogenesis in humans and animals.
*830. Veterinary Anatomy I (VMED 630) (6 cr I) Lec 3, lab 6.
Prereq: For VBMS *830: none. For VMED 630: First year standing in the Professional Program in Veterinary Medicine
Comparative and topographic anatomy of the dog, cat, and pig.
*835. Animal Biochemistry (BIOS *835) (3 cr II, even-numbered years) Lec/disc.
Prereq: BIOC 831 or permission
Biochemistry of animal cells and tissues, with integration of major metabolic pathways and aspects of their control mechanism.
840. Microbial Physiology (BIOS 840) (3 cr) Lec 3.
Prereq: BIOS 312 and either 313 or 314; or permission
Molecular approaches to the study of prokaryotic cell structure and physiology, including growth, cell division, metabolism, and alternative microbial life styles.
841. Pathogenic Microbiology (BIOS 841) (3 cr II) Lec 3.
Prereq: BIOS 312 and either 313 or 314, or permission
Fundamental principles involved in host-microorganism interrelationships. Identification of pathogens, isolation, propagation, mode of transmission, pathogenicity, symptoms, treatment, prevention of disease, epidemiology, and methods of control.
841L. Pathogenic Microbiology Laboratory (1 cr II)
Prereq: BIOS 312 and 313 (314) or permission
Application of diagnostic microbiological techniques to the isolation, propagation and identification of common pathogens of human beings and animals. Case studies used, in the laboratory setting, to explore and test fundamentals of transmission, epidemiology and to disease pathogenesis of selected infectious agents and to relate these to disease signs, treatments and methods of control.
842. Endocrinology (ASCI 842; BIOS 842) (3 cr I) Lec 3.
Prereq: A course in vertebrate physiology and/or biochemistry
Mammalian endocrine glands from the standpoint of their structure, their physiological function in relation to the organism, the chemical nature and mechanisms of action of their secretory products, and the nature of anomalies manifested with their dysfunction.
843. Immunology (BIOS 843) (3 cr) Lec.
Prereq: BIOS 206 and one semester organic chemistry
BIOS 201 recommended. A fundamental consideration of cellular and humoral mechanisms of immunity, the structure and function of immunoglobulins, antigen-antibody interactions; hypersensitivity; transplantation and tumor immunity; immune and autoimmune disorders.
*845. Animal Physiology I (ASCI *845; BIOS *813; VMED 645) (4 cr I) Lec 3, lab 3.
Prereq: For ASCI/VBMS *845/BIOS *813: An undergraduate course in biochemistry or biology or physiology. For VMED 645: First year standing in and admission to VMED.
Primarily for students in animal or biological sciences or veterinary medicine.
Mammalian physiology and cellular mechanisms. Physiology of the cell, embryology, and neuro-sensory, neuromuscular, endocrine, and reproductive systems.
*846. Animal Physiology II (ASCI *846; BIOS *814; VMED 646) (4 cr II) Lec 3, lab 3.
Prereq: For ASCI/VBMS *846/BIOS *814: An undergraduate course in biochemistry or biology or physiology. For VMED 646: First year standing in and admission to VMED.
ASCI/VBMS *846/BIOS *814/VMED 646 is designed for students in animal or biological sciences or veterinary medicine.
Mammalian physiology and cellular mechanisms. Physiology of the digestive, cardiovascular, respiratory, and renal systems.
*847. Interdisciplinary Concepts in Beef Production (ASCI *847) (3 cr, max 6)
Prereq: Degree in veterinary medicine or animal science, or allied agricultural degree, or permission
Classroom attendance is required during each of the modules. Between modules distance education technologies (laptop computer, Internet access, a computer operating system with a word processor, spreadsheet, and presentation software, email, etc.) are used and required for discussion and assignments. The contributions and interactions of the major academic disciplines upon the production, performance, health, profitability, and sustainability of beef cow and cattle feeding operations.
A. I (3 cr)
B. II (3 cr) Prereq: VBMS *847A.
847A. Interdisciplinary Concepts in Beef Production I (3 cr)
847B. Interdisciplinary Concepts in Beef Production II (3 cr)
Prereq: VBMS *847A
*848. Introduction to Veterinary Biotechnology (1-2 cr)
Prereq: 12 hours of veterinary and biomedical sciences or DVM degree, or equivalent and permission
Information and assignments for VBMS 848 exchanged in the classroom and via Internet. Theoretical basis for emerging cellular, molecular and reproductive technologies, and their potential applications and impacts in the practice of food animal veterinary medicine.
*852. Molecular Virology and Viral Pathogenesis (3 cr I) Lec 3.
Prereq: BIOS 843
Offered even-numbered calendar years. Introduction to virology with emphasis on molecular biology and pathogenesis. Concepts of virus replication strategies, virus-host interactions and virus pathogenesis.
*899. Masters Thesis (6-10 cr)
Prereq: Admission to masters degree program and permission of major adviser
901. Diagnostic Techniques (1-10 cr)
Application of the principles of pathology to current problems in the diagnostic laboratory.
908. T Cell Biology: Repertoire and Effector Functions (3 cr I)
Prereq: BIOS 843 or permission
Offered even-numbered calendar years. Analysis of the literature of the cellular and molecular biology of T cell recognition and effector functions. Subject areas: Scientific Methodologies; Antigen Presentation; T Cell Receptor and Coreceptor; Thymic Structure and Self/Nonself Discrimination; T Cell Regulation; Allergy and Autoimmune Diseases; and T-Cell-Mediated Inflammation and Cytokine Network.
909. Seminar (1-4 cr I, II)
P/N only.
919. Regulation of Eukaryotic Gene Expression (3 cr II) Lec 3.
Prereq: 1) BIOC 818 or 820; 2) BIOC 832; and 3) BIOC 838 or BIOS 837 or related laboratory experience
Offered even-numbered calendar years. Basic mechanisms regulating gene expression in eukaryotes during various physiological states. Emphasis on understanding specific and unique mechanisms in mammalian systems. Techniques used to study gene regulation.
920. Measurement of Animal Disease and Production (2 cr I) Lec/disc and lab.
Prereq: VBMS *811 or permission
Offered odd-numbered calendar years. Measurements of disease and production, the basic tenants of epidemiology, taught in detail including incidence density, risk rates, morbidity, mortality, cause specific rates, and life tables. Methods and implications of measuring disease at the farm, regional, and national levels. Sampling strategies and the impact of these on the standard error of the estimate. Implications and biases of using retrospective production data versus prospective data. Clinical epidemiology which includes definition of tests in veterinary medicine, individual and herd level sensitivity and specificity, receiver operating characteristics curves, positive and negative predictive values, serial and parallel interpretation of tests, Kappa statistics, and issues of precision, validity, and accuracy.
921. Analytic Observational Studies in Veterinary Epidemiology (2 cr I) Lec/disc & lab.
Prereq: VBMS *811 and 920; or permission
Offered odd-numbered calendar years. Design, implementation, and analysis of cross-sectional, cohort, and case-control studies and field trials. Limitations, biases, implications of the results, and current uses of each. Evaluation of these methods as used in the scientific literature. Analyses includes chi-square tests, Cochrane Chi-square tests, and epidemiologic measures of strength of association, effect, and total effect. Design, implementation, analysis and interpretation of field trials taught specifically as they relate to the practitioner.
925. Critical Reading of the Epidemiology Literature (1 cr, max 4)
Prereq: VBMS *811 or 920; or permission
May be repeated for credit. Analysis of current epidemiology and animal health literature. Critical evaluation of study design, methods of analysis, biases, field applicability, and basis for conclusions.
930. Advanced Food Animal Production Medicine (2 cr) Lec/disc & lab.
Prereq: Permission
Offered spring semester of even-numbered calendar years. Inter-relationships between animal health, disease, and well-being as they relate to the productivity and profitability of food animal production units. Integrates aspects of veterinary medicine, animal science, and agricultural economics. General concepts related to cattle, swine and sheep production systems, followed by specific issues that relate to different species.
942. Genetics, Genomics, and Bioinformatics of Prokaryotes (BIOS 942) (3 cr)
Prereq: BIOS 241 and 312, or permission
Prokaryotic gene regulation, DNA exchange, DNA recombination and repair, comparative prokaryotic genomics and computer-based methods of analysis.
944. Immunovirology (3 cr) Lec 3.
Prereq: Permission; organic chemistry; biochemistry; immunology and/or concepts in virology and virolopathogenesis
Pathogenic microbiology recommended. Description of virus and immune system interactions, with emphasis on mouse and human models. Mechanism of antigen presentation of viral proteins and relationship to health and disease. Analysis of the hosts immune response to selected viral infections of the major systems: neural, respiratory, gastrointestinal and immune.
948. Concepts in Experimental Immunology (3 cr II) Lec 3.
Prereq: BIOS 843 or permission
Recent advances in immunological techniques and review of conventional methods.
949. Vaccinology (2 cr) Lec/disc.
Prereq: VBMS/BIOS 841; BIOS 843, VBMS 843; VBMS/BIOS 852; or permission
Analysis of the theory and mechanisms involved in the development of efficacious vaccines. Microbiological and immunological aspects as well as the manufacturing and regulatory aspects of vaccine development.
950. Medical Molecular Virology (BIOS 950) (3 cr I) Lec.
Prereq: BIOS/CHEM/BIOC 431/831 and 432/832; VBMS *852
Offered odd-numbered calendar years. Current topics in molecular virology relevant to the natural history and pathogenesis of viral diseases of humans and animals.
951. Advanced Molecular Infectious Diseases (3 cr II) Lec 3.
Prereq: BIOC 832 or equivalent; 18 hours of biological, biomedical and/or veterinary sciences, including fundamental microbiology and genetics; or permission
VBMS 824 and 843 or equivalent recommended. Offered spring semester of even-numbered years. Molecular and cellular aspects of microbial pathogenesis. Key literature, synthesis of scientific problems into research proposals.
964. Signal Transduction (BIOS 964) (3 cr)
Prereq: BIOS 832, BIOS 820 or equivalent, or permission
Molecular basis of genetics in eukaryotes. Gene structure and regulation, transposable elements, chromosome structure, DNA replication and repair mechanisms and recombination.
966. Advanced Viral Pathogenesis (BIOS 966) (3 cr)
Prereq: BIOS 843; VBMS 852 or equivalent introductory course in virology or experience
Advanced analysis on the mechanisms of cell and tissue damage by viruses, the spread of viruses through the body, and the host response.
975. Seminar in Veterinary Histopathology (1 cr I, II) Lec 1.
Prereq: VBMS 805, or equivalent and permission
May be repeated for credit. Descriptive veterinary histopathology covering diseases of all body systems in animal species including domestic, laboratory, wildlife, birds, fishes, reptiles, and amphibians. Source material is worldwide in scope.
996. Research on Selected Problems in Veterinary Science (2-10 cr)
998. Special Topics in Veterinary Science (1-10 cr)
Prereq: Permission
The subject will be dependent on student demand and availability of staff. Reviews of specialized subject areas.